Introduction: Timing and Teamwork Save Lives When cardiac arrest strikes, every second counts. The seamless integration of the Automated External Defibrillator (AED) application during two-rescuer CPR represents one of the most significant advancements in modern resuscitation science. Research demonstrates that for every minute defibrillation is delayed, survival rates decrease by 7-10%. Proper AED application combined with high-quality CPR can more than double a victim's chance of survival when compared to CPR alone. This comprehensive guide examines the critical relationship between AED application and two-rescuer CPR, providing healthcare professionals and trained responders with evidence-based protocols that optimize outcomes. From initial assessment to post-resuscitation care, understanding these best practices ensures rescuers can act with confidence and precision during life-threatening emergencies. Understanding AED Integration in the Chain of Survival The American Heart ...